Views:1 Author:Site Editor Publish Time: 2021-08-27 Origin:Site
Glutathione is a short peptide of three amino acids found in almost every cell of the body. However, glutathione must be produced by cells and its precursors (vitamin C and alpha-lipoic acid) to function effectively in the body. The presence of glutathione is required to maintain normal immune system function. It is already known to play a key role in the reproduction of lymphocytes (cell-mediated specific immunity) that occurs in the development of an effective immune response. In addition, cells in the immune system produce many oxiradicals due to their normal operation and therefore require a higher concentration of antioxidants than ordinary batteries. Glutathione plays an important role in achieving this requirement.
Boosting the human immune system Your body's immune activity involves multiplication of unblocked lymphocytes and antibody production required to maintain normal levels of glutathione intracellular lymphocytes. The antioxidant and free radical scavenger glutathione has cyclic protective effects on bacteria, viral contaminants and free radicals. Regulate other antioxidants - Glutathione Other important antioxidants such as vitamins C and E don't do their job well enough to protect your body from disease.
Glutathione is a small peptide containing sulfhydryl group, which has two important antioxidant and integrative detoxification effects. Glutathione is a tripeptide formed by the combination of glutamic acid, cysteine and glycine. The sulfhydryl group on cysteine is its active group (so glutathione is often short for G-SH). It is easy to complex with iodoacetic acid, mustard gas, lead, mercury, arsenic and other heavy metal salts, and has an integrated detoxification effect. Glutathione (particularly liver intracellular GSH) has very important physiological function is to integrate detoxification, with certain drugs, such as paracetamol, toxins (such as free radicals, heavy metals), participate in bioconversion, harmful to the body of toxins into harmless substance, drain out of the body.
reduced glutathione (G-SH) and oxidized glutathione (G-S-S-G), and reduced glutathione predominates in physiological conditions. Tautometry between two types catalyzed by glutathione reductase.The coenzyme provides NADPH for sugar phosphate bypass metabolism.
Another major physiological function of glutathione is as an important antioxidant in the body, which can remove free radicals from the body and clean up and purify the environment, thereby improving physical and mental health. Because glutathione is itself susceptible to oxidation by certain substances, it protects the sulfhydryl groups in many proteins and enzymes in the body from oxidation by harmful substances such as free radicals, allowing them to perform their physiological functions.
There is a lot of glutathione in human red blood cells, which is of great significance to protect the thiol group of protein on the red cell membrane in the reduced state and prevent hemolysis. Moreover, it can also protect hemoglobin from oxidation by hydrogen peroxide, free radicals and other oxidation, so that it can continue to play the normal capacity of oxygen transport. Under the action of oxidizing agent such as hydrogen peroxide, part of hemoglobin in red blood cells oxidizes to trivalent iron, so that hemoglobin is transformed into methemoglobin, thus losing the ability to carry oxygen. Reduced glutathione can not only directly combine with oxidants such as hydrogen peroxide to form water and oxidized glutathione, but also reduce methemoglobin to hemoglobin.
In addition, vitamin C is an important antioxidant in the body. Because vitamin C can be reversibly hydrogenated or dehydrogenated, vitamin C plays an important role in many REDOX reactions in the body. For example, the active group of many enzymes is sulfhydryl group (-- SH), and vitamin C can maintain the activity of enzymes by maintaining the reduction state of -- SH. Vitamin C can transform oxidized glutathione into reduced glutathione (GSH) and reduce H2O2 produced by metabolism. Vitamin C also protects vitamins A and E and certain B vitamins from oxidation. Therefore, glutathione can be used in combination with vitamin C to increase its efficacy.